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68 Similarly, deletion of Atg7 or LAMP2 leads to cardiomyopathy with mitochondrial defects, 67 thus emphasizing the vital link between autophagy and mitochondrial health

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PD and several related neurodegenerative disorders can also been considered as proteinopathies, in which the core neurodegeneration of nigrostriatal dopaminergic neurons in PD is also associated with a more widespread cellular deposition of alpha-synuclein 8