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Journal of Robotic Surgery

Additionally, HMGB1 enriched in NETs binds to the CXCL12 receptor to activate CXCR4, inducing HSCs to transform into myofibroblasts and promoting collagen deposition via the TGF-/Smad3 pathway (120, 121)

By reducing joint pain and accelerating injury recovery, it enables patients to comfortably maintain the active, exercise-rich lifestyle necessary for shedding pounds