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They are distinctly not drugs of first choice compared to methotrexate (MTX) and tumor necrosis factor (TNF) inhibitors (Cohen, 2023)

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(2019) NAD+ in brain aging and neurodegenerative disorders

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The results also indicated that only MAF (minor allele frequency) values of 0.467, 0.011 and 0.422 showed relatively strong linkage disequilibrium

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