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En un estudio clnico multicntrico europeo, la suplementacin con L-carnitina (en forma de propionil-L-carnitina a 2 g/da durante 12 meses) en pacientes con claudicacin moderada a severa relacionada con la distancia mxima recorrida y la calidad de vida percibida logr una mejora significativa en comparacin con los pacientes que solo recibieron placebos

Future study is needed to determine what, if any, physiologic benefit is associated with the observed increase in plasma NOx with GPLC supplementation

While secondary outcomes should be interpreted cautiously in the face of overall non-significant results for the primary outcome, our findings suggest potential harm with L-C supplements, both for worsening cardiometabolic risk factors (i.e., LDL-C) and for atherosclerosis progression (i.e., stenosis)

Comparison of the Metabolic Profiles in the Plasma and Urine Samples Between Autistic and Typically Developing Boys: A Preliminary Study