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Of course we cant know if this imposed reduced frequency had any impact however the word pernicious springs to mind

These include mutations in genes such as: SNCA Alpha-synuclein gene PRKN Parkin RBR E3 Ubiquitin Protein Ligase PINK1 Gene PARK6 DJ-1 and PARK7 Gene LRRK2 It is believed that mutations in these genes can cause dysfunction and eventual death of dopamine-producing neurons through various mechanisms, including protein aggregation, mitochondrial dysfunction, and oxidative stress

Moreover, some mRNA and viral vector vaccines can induce Th1 cell responses 19,20 and persistent human germinal center responses, 21,22 which provide more efficient protection

We need to hear from Shot #2 folks