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Proceedings of the National Academy of Sciences of the United States of America 105, 18782-18787

Selectivity: Because Ipamorelin doesnt spike cortisol, it avoids a major compounding factor

FDAs evaluation states them precisely: positions 2, 8, 15 and 27 of GHRH(1-29), natively L-alanine, L-asparagine, L-glycine and L-methionine , were substituted to D-alanine, L-glutamine, L-alanine and L-leucine respectively [11]