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The role of ABC transporters in progression and clinical outcome of colorectal cancer

(A, B) Serum levels of ALT (A) and AST (B) were measured at different timepoints after APAP challenge

Canat A, Atilla D, Torres-Padilla M

Four main mechanisms have been identified for the induction of ferroptosis, including hindering system xc , inhibiting, degrading, or inactivating GPX4, depleting reduced Coenzyme Q10 (CoQ10), and triggering LPO via peroxides, iron, or PUFA overload (Stockwell, 2022)