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In 5-FU resistance, serine deprivation restores chemosensitivity, and metabolite supplementation recapitulates resistance

Establishing a Regimen For those starting on B12 shot, the regimen typically begins with a series of loading doses to quickly raise B12 levels

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Indeed, we have previously shown that vitamin B12 (vB12, cyanocobalamin) treatment ameliorates some of the heart and brain abnormalities observed in Tbx1 mutant embryos and adult mice (13, 14, 15), suggesting that it acts downstream of Tbx1