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Interventions that focused on enhancing balance and coordination, which are essential for rehabilitation, showed that training with the Biodex Balance System can improve DPN patients static balance and coordination, underscoring the possibility of using targeted physical therapy to lessen functional impairments (102)

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We found that a considerable number of proteins and metabolites were both involved in mineral absorption, proximal tubule bicarbonate reclamation, inflammatory mediator regulation, lysosome, neuroactive ligand-receptor interaction, cAMP signaling pathway, biosynthesis of amino acids, purine metabolism, fructose and mannose metabolism, glycolysis/gluconeogenesis Fig