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The much larger, headline-grabbing numbers associated with cagrilintide in the press figures in the low-to-mid 20% range come from Phase 3 trials of CagriSema , the combination with semaglutide, and are company-reported topline results, not standalone-cagrilintide data and not the peer-reviewed Phase 2 result cited above

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Using APP/PS1 mice as subjects, researchers found that the monoterpene glycoside paeoniflorin (PF) improved cognitive performance and downregulated the levels of Fe 2+ , MAD, and ROS in brain tissue, which reduced oxidative damage and thus alleviated the neurological damage in AD mice (Zhang and Wei, 2020

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