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Body Composition-Based Dosing Calculations More sophisticated researchers may utilize body composition data to refine dosing: For individuals with lower body fat percentages (under 15% for males, under 25% for females): Starting dose: 0.25-0.35mg per kg body weight Maintenance dose: 0.35-0.45mg per kg body weight For individuals with higher body fat percentages : Starting dose: 0.35-0.45mg per kg body weight Maintenance dose: 0.45-0.55mg per kg body weight These calculations provide a more personalized starting point than standard ranges, though individual response still necessitates adjustment

Administration Guidance Detailed instructions and support are provided to ensure you can use your medication safely and effectively

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Mirikizumab pharmacokinetics in patients with moderately to severely active ulcerative colitis: results from phase III LUCENT studies