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The system biology of thiol redox system in Escherichia coli and yeast: differential functions in oxidative stress, iron metabolism and DNA synthesis

"We know that when oxidation tips the balance toward too much GSSG, we get a redox potential shifted more to the positive than it should be," Reipa explains

Although prolonged treatment with oral N-acetylcysteine (NAC) prevents acute exacerbations of chronic bronchitis, it remains controversial for the treatment of COPD (91, 103105)