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[117] demonstrated that dapagliflozin provides direct cardiac protection by suppressing the NHE1/mitogen-activated protein kinase/activator protein-1 pathway-mediated inflammatory response in cardiomyocytes, reducing proinflammatory macrophage infiltration in the cardiac tissue of HF mice

It is important (if deciding to move forward and take a collagen supplement) to have it sourced from grass-fed or organic animals