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Jewell et al., 2015) via the small GTPase ADP-ribosylation factor 1 (ARF1) (Jewell et al., 2015)

This protective effect is attributed to the ability of Lactobacillus casei Shirota (LcS) to stimulate the secretion of TNF- and interleukin-12 (IL-12), cytokines that are well-established drivers of enhanced NK cell cytotoxic activity (194)