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Esta modulacin amplia de la expresin gnica es caracterstica de los pptidos biorreguladores compuestos cuyo modo de accin primario implica influir en los programas transcripcionales que gobiernan el comportamiento celular

In the cortex, both the percentage area of A plaques and the levels of soluble A 140 , A 142 , and A oligomer were significantly reduced in the combination group than in the (-)-Vestitol group ( P = 0.0391, 0.0041, 0.0471, and 0.0425, respectively) and the Salviolone group ( P = 0.0166, 0.0005, 0.0115, and 0.0132, respectively) (Fig

17 18 In addition, cell studies indicate Alzheimers disease may be linked with lower DNA methylation, 19 and mitochondrial dysfunction is widely considered an important driver in Alzheimers disease development