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Under oxidative conditions, the redox-sensitive enzyme SUMO-specific protease 3 (SENP3) accumulates in Tregs and mediates the deSUMOylation of BTB domain and CNC homolog 2 (BACH2), a transcription factor that stabilizes Treg identity [12]

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Understanding TBI, Part 2: Brain injury impact on individuals functioning Understanding TBI, Part 4: The impact of a recent TBI on family members and what they can do to help with recovery Understanding TBI was developed by Thomas Novack, PhD and Tamara Bushnik, PhD in collaboration with the Model System Knowledge Translation Center