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MacLaren Walsh, J

DHODH holds a pivotal position in the biosynthetic pathway of pyrimidine nucleotides, playing a crucial role in the production of DNA and RNA (49), Inhibition of DHODH disrupts this pathway, leading to abnormalities in, or cessation of, pyrimidine nucleotide synthesis

L-Glutathione (Reduced) Acts as a major intracellular antioxidant, neutralizing free radicals and reactive oxygen species

A landmark series of European trials including the ALADIN, SYDNEY, and NATHAN studies investigated oral ALA supplementation at 600 mg per day and found meaningful results in supporting peripheral nerve comfort and function