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These results of the wet macular degeneration treatment using Lucentis represented a breakthrough compared to the natural history of the disease, which essentially leads to legal blindness in the vast majority of patients

For example, heparinase, an enzyme that degrades heparan sulphate and enhances the invasive and metastatic capacity of cancer cells, was reported to be activated by s -cysteinylation

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However, under the controlled, reproducible conditions of mycelial cultures, the differences in the amounts of bioactive compounds, such as polysaccharides, terpenoids, steroids, and phenolic compounds, are significantly reduced (SulkowskaZiaja et al