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Description

Regular physical exercise modulates iron homeostasis in the 5xFAD mouse model of Alzheimers disease

Although, to date, a complete understanding of physiological conditions that may create reductive stress have not been elucidated, conditions, such as hypoxia, hyperglycemia, and other stresses that inhibit mitochondrial function, are known to cause excess accumulation of cellular reducing equivalents (199, 270, 358)