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Furthermore, IL-22-induced claudin-2 upregulation can drive diarrhea and pathogen clearance [90]

The translation of UA from murine models to human clinical efficacy is still the final obstacle to its approval as a potential AD treatment, even if these findings provide a strong molecular basis

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Alterations in regulatory components of NOX2 results in generation of phagocytic oxidative stress and phagocytic burst to eliminate enclosed pathogen [58]