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Whats more, the studies of brodalumab, a humanized monoclonal antibody that binds to IL-17RA, was stopped because of the relative lack of efficacy in the initial asthma clinical trial and a questionable safety issue (58)

,* Shyh-Chang, N.,* Segr, A.V., Shinoda, G., Shah, S.P., Einhorn, W.S., Takeuchi, A., Engreitz, J.M., Hagan, J.P., Kharas, M.G., Urbach, A., Thornton, J.E., Triboulet, R.,nGregory, R.I

Inserted into bone marrow cavity of femur with a 20 mL syringe, flushed bone cavity with sterile PBS until the bone marrow was rinsed thoroughly

Maxwell Chamberlain Memorial Paper for General Thoracic Surgery, 2018