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Mathew PM Managing the Child with Severe Primary Insulin-Like Growth Factor-1 Deficiency (IGFD): IGFD Diagnosis and Management

PubMed Central , Kruse, Andreas O., and Juan R

To address this, we created a floxed SHMT2 mouse allele (SHMT2 fl/fl ) with two loxP sites spanning exons 312, allowing for conditional targeting by lox/Cre recombination (Fig