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NAD+ levels decline 15-65% with age across tissues , triggering DNA damage, mitochondrial dysfunction, and cellular senescence that accelerate aging processes

The classic presentation of thiamine deficiency is known as beriberi, which is characterized by nerve involvement and can lead to symptoms such as ataxia, oculomotor abnormalities, and aphonia

It is believed that the algorithms that will be created by analyzing imaging features and patient-specific parameters will increase the accuracy of HT diagnosis