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Ann Oncol 30(10):1580-1590, 2019

in other words, under the normal redox conditions of the ER lumen, ERdj5 exists almost exclusively in the oxidized form and acts only as a reductase

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Using the FiLa lactate probe, researchers observed lactate enrichment in the nuclei of two-cell embryos an determined that it was critical for preimplantation development