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Studies suggest that palmitoylation of GLT-1 is important for glutamate uptake capacity, as a reduction in palmitoylated GLT-1 leads to impairments in glutamate clearance [137]

Location USF Health Byrd Institute 4001 Fletcher Avenue, 6th Floor Tampa, FL 33613 Clinical Trials A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease (PARAISO) ID: NCT07174310 Brief Summary: The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of prasinezumab compared with placebo in participants with early-stage Parkinson's disease (PD) on stable symptomatic monotherapy with levodopa

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Bronchial epithelial SIRT1 deficiency exacerbates cigarette smoke induced emphysema in mice through the FOXO3/PINK1 pathway