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The problem here is not the production of free radicals, but rather their abnormal and excessive production under conditions such as stress

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Chen G, Han Y, Zhang H, Tu W, Zhang S

novel cancer therapeutics can also be assessed Well-characterized PDTX models represent an information-rich preclinical resource for analysis of drug activity, including novelnovel drug combinations, as well as predictive biomarker discovery The PDTX approach to modelling of specific cancer types could potentially reduce non-informative animal studies while providing a more-relevant system to test clinically directed hypotheses This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access 189,00 per year only 15,75 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF