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A chemical probe to directly modulate the incorporation of TRF1 into shelterin would be a valuable tool to interrogate telomere maintenance mechanisms and a potential starting point for the development of novel anti-cancer therapeutics targeting the shelterin complex

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~ AlphaMD Many people associate nicotine primarily with smoking and tobacco use, but with the growing popularity of nicotine gum, patches, and other alternatives, questions arise about how nicotine itself affects the body

What TB-500 Brings to the Protocol TB-500 is thymosin beta-4, a 43-amino acid peptide that occurs naturally in human tissue, with high concentrations in platelets, wound fluid, and the heart