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RESEARCH AREAS NNMT enzyme inhibition characterized in published literature for selective NNMT inhibition in vitro

Escolar ML, Poe MD, Provenzale JM, Richards KC, Allison J, Wood S, et al

Next, Cys58 nucleophilically attacks the sulfide of Cys58, releasing a GS- anion, which picks up a solvent proton and is released from the enzyme, forming the second GSH