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The trans-3-hexenoic acid modification provides DPP-4 resistance, substantially extending the practical research half-life vs native GHRH

Over-the-counter options like topical retinoids, alpha hydroxy acids (AHAs), lactic acid, salicylic acid, and daily sunscreen may help scars look less noticeable over time

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It can also be considered in cases of resistant melasma or recurrent melasma