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Nanocarriers have been shown to have a transient effect on targeted transporter plasma membrane localization as, after binding, the nanocarrier-transporter complex is internalized in the cell followed by recycling of the transporter back on the plasma membrane (82)

54 In contrast to the negative effects of reprogramming T-cell lipid metabolism on antitumor immunity, the inhibition of ACAT1, a pivotal enzyme responsible for cholesterol esterification in CD8 + T cells, results in elevated cholesterol levels in the plasma membrane

Fei H, Qian Y, Pan T, Wei Y, Hu Y (2024) Curcumin alleviates hypertrophic scarring by inhibiting fibroblast activation and regulating tissue inflammation