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Journal of Spinal Disorders and Techniques, 15 , 157163

Human safety data is insufficient to make any definitive statement about long-term use, with no large-scale toxicology or long-term safety trials in humans performed as of this writing

5-Amino-1MQ is a small molecule derivative studied as a nicotinamide N-methyltransferase (NNMT) inhibitor

Ab68 may exert its anti-inflammatory effects by preventing CD38 from binding to its cognate receptor CD31, thereby reducing CD38 + immune cell adhesion to endothelium and CD31-mediated transmigration to sites of inflammation 52,56,57