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Under the electron microscope, the ultrastructural damage of cells was obvious, the intracellular apoptotic bodies increased, the nucleolus lobules increased, the nuclear membrane was blurred and unstructured, the mitochondria showed obvious swelling, and the mitochondrial crest fracture disappeared, showing early or late apoptotic manifestations

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Like carnitine, ALA is naturally present in the human body, and is essential for the function of several enzymes involved in mitochondrial energy generation

Acknowledgments We would like to thank the participants in the study and their families