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Mucosal Immunol 10:15531568 Matarrese P, Straface E, Pietraforte D et al (2005) Peroxynitrite induces senescence and apoptosis of red blood cells through the activation of aspartyl and cysteinyl proteases

In addition, the ratio of reduced glutathione to oxidised glutathione (GSH/GSSG) was significantly increased, and the expression of malondialdehyde (MDA), a biomarker of iron metabolism indicative of lipid peroxidation, was also significantly reduced after FEV knockdown (Figures 4B,C)