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This data can be accessible at: Abbreviations ADA: American Diabetes Association ALP: Alkaline phosphatase BMC: Bone mineral content BMD: Bone mineral density CDC: Centers for Disease Control and Prevention DAVID: Database for Annotation, Visualization and Integrated Discovery DXA: Dual-energy X-ray absorptiometry FAD: Flavin adenine dinucleotide FMN: Flavin mononucleotide GO: Gene Ontology GSH: Reduced glutathione GSSG: Oxidized glutathione KEGG: Kyoto Encyclopedia of Genes and Genomes MEC: Mobile Examination Center MET: Metabolic equivalent task NHANES: National Health and Nutrition Examination Survey PA: Physical activity PPIs: Protein-protein interactions RCS: Restricted cubic spline References Ensrud KE, Crandall CJ, Osteoporosis

Specifically, GABA decreased in OTC for the signal-from-noise task, indicating that disinhibition could facilitate the extraction of feature from noise, potentially through an amplification of neuronal gain

Importantly, voluntary exercise improved hepatic steatosis (liver triglyceride, H&E staining, and Oil red-O staining) and fibrosis (serious-red staining) in both CD and WD fed mice

Limiting the GSH formation by inhibiting system x c - is a promising approach to kill tumor cells due to the excessive active metabolism and sustained oxidative stress [43]