glutathione stores in liver Dysregulation of synthesis disease Glutathione in the tumor and

elegans (wild-type N2) were obtained from Caenorhabditis Genetics Center (CGC) and cultured on sterilized growth medium plates (NGM: 3.0 g/L NaCl, 2.5 g/L peptone, 17.0 g/L agar, 7.75 g/L potassium phosphate, 0.11 g/L CaCl 2 2H 2 O, 0.24 g/L MgSO 4 7H 2 O, and 1 mL cholesterol) at 20 C

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Supplementary Figure 1 No changes of renal morphology and function in the healthy mice after oral medications of LA (50 or 100mg/kg)

High-protein diets can increase renal metabolic burden and promote the generation of harmful metabolites derived from intestinal protein fermentation, while Western dietary patterns characterized by high fat and sugar intake are closely associated with insulin resistance, chronic low-grade inflammation, and gut microbiota dysbiosis (7)