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As CD38 is expressed on the surface of early OC precursors, CD38 blocking may also prevent early OC formation [43]

In experimental models it is used to explore mechanisms of tissue regeneration, angiogenesis, inflammatory modulation and maintenance of gastrointestinal barrier integrity

In one double-blinded controlled study of ALA therapy for BMS, there was a significant improvement in pain, compared with placebo, with the majority of test subjects showing some improvement after 2 months, and more than 70% of the subjects maintained this improvement at 1 year