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The Activation of the NF-b-JNK Pathway Is Independent of the PI3K-Rac1-JNK Pathway Involved in the bFGF-Regulated Human Fibroblast Cell Migration

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Bottom: volcano plot showing relative fold change (log 2 ) in whole cell metabolite abundance versus log 10 (P value) from ER-tag HEK293T cells treated with thapsigargin compared to untreated

Similarly, activated microglia contribute to oxidative stress by upregulating NADPH oxidase 2 (NOX2), which generates O , and inducible nitric oxide synthase (iNOS), which produces nitric oxide (NO)