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The answer depends on the patients diagnosis, goals, risk factors, medication history, sports rules, available evidence, and whether a medically supervised plan is appropriate

Lin Z, Yu S, Yang Y, et al (2024) The double-edged effects of substance P in the pathology of Alzheimers disease

Combination therapy can add complexity because semaglutide has its own GI side-effect profile, and overlapping appetite and gastric-emptying effects can be clinically meaningful