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Regulation of Cyp3a gene transcription by the pregnane x receptor

Pregnancy and breastfeeding: There is insufficient safety data for peptide use during pregnancy or lactation

This guide presents a comprehensive MOTS-c dosage chart and week-by-week titration protocol, grounded in the published literature, to help clinicians and educated patients understand both the rationale for dosing decisions and the practical parameters of a safe, evidence-informed approach

Muoz for assistance with the animal protocols, to the IRB Functional Genomics Unit and CRG/CNAG for library preparation and genomic sequencing, and to the IRB (Functional Genomics, Biostatistics/Bioinformatics, and Histopathology) and PCB (Animal House) core facilities for general research support