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Also, in this work, the authors observed that in cortical neurons treated with 6-hydroxydopamine, paeonol attenuated the production of ROS, increased the activity of SOD1 and the expression of the antiapoptotic protein B-cell lymphoma 2 [181]

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Their propensity for self-assembly originates principally from their amphiphilic structure: the hydrophobic aglycone core mediates molecular aggregation via hydrophobic interactions, while the hydrophilic sugar chains facilitate hydration shell formation and participate in hydrogen bonding