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Originally designed as an intra-articular injection, it has also shown potent effects as a subcutaneous injection, and it is one of the only agents that has been shown to strengthen cartilage tissue by increasing cross-linking and polymerisation of the large molecules found in cartilage: (79) (80) (81) (82) (83) (84)

Preparation We gently clean the area, removing any product, oil, or buildup

It reduces trans-epidermal water loss and improves moisture retention of the skin