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Abatacept treatment for patients with early active primary sjgrens syndrome: a single-centre, randomised, double-blind, placebo-controlled, phase 3 trial (Asap-iii study)

For effective mechanical and chemical digestion of food, absorption of nutrients in the small intestine, calorie supply for cells, and elimination of waste through defecation, both the organs of the digestive tract and accessory structures such as the liver, pancreas, and gallbladder must work together in harmony

Secondly, the ROS attack accelerates apoptosis of retinal tissues and cells and aggravates DR, 68 with the activated polyol pathway, hexosamine pathway, and PKC pathway, as well as advanced glycation end products (AGEs) accumulation involved in the process