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Ask your doctor if you are pregnant, or plan to become pregnant, or if you are breastfeeding before having a B12 shot

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The most common vitamin B12 deficiency symptoms are: Fatigue Weakness Loss of appetite Weight loss Numbness and tingling in the hands and feet Soreness of the mouth or tongue A pale yellow tinge to your skin Difficulty maintaining balance Disturbed vision Depression Confusion Poor short-term memory A severe vitamin B12 deficiency can cause megaloblastic anemia, also known as vitamin B12 deficiency anemia, where red blood cells are not produced properly and are larger than normal

You may be instructed to discontinue certain medications that affect the clotting of your blood several days before the injection