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Tocilizumab (a type of IL-6 receptor inhibitor, IL-6R), first licensed to rheumatoid disorders, could successfully cure iatrogenic cytokine storms in patients with hematological malignancies produced by CAR-T therapy (Grupp et al., 2013)

Moreover, the immunogenicity response of GX-G3 was lower in monkeys than in rats, which was relevant to show less inhibition of toxicokinetic profiles in monkeys, at least 1 mg/kg administrated group, compared to rats

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However, individuals from a high fishing eating population from Brazil with TT genotype had lower hair and plasma THg concentrations [40]