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Gagnerault, Tsumetoshi Itoh, J

For example, the clustering of mitochondria in dendritic spines in response to neural activity may be altered (Li et al., 2004)

time profiles as described 19 : maximum plasma concentration ( C max ), time to reach C max ( t max ), terminal elimination rate constant ( z ), terminal elimination half-life ( t 1/2 ), area under the plasma concentration-time curve (AUC) from time zero to the time of the last measurable concentration (AUC last ), AUC from time zero to infinity (AUC inf ), oral clearance (CL/F), and apparent volume of distribution during the terminal phase (V z /F)

Research protocols have used multiple administration routes, including intraperitoneal, subcutaneous, intramuscular, intravenous, and oral delivery , strictly within preclinical research settings