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These challenges include safety concerns, drug specificity, delivery methods, off-target effects, long-term consequences, and regulatory hurdles

10.1074/jbc.M303620200 39 DroogF.SpekA.van der KooyA.de RuyterA.HogeH.LibbengaK.et al

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Ox-LDL also stimulates the release of monocyte-derived tumoral necrosis factor alpha (TNF-) and interleukin 1 beta (IL-1), leading to smooth muscle cell proliferation