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Whilst the effect of Vitamin B12 on mood is not yet fully understood, it plays a vital role in the synthesis and metabolism of serotonin the chemical responsible for regulating your mood

Biochem Res Int 2017

Glutathione in the Brain states, GSH depletion in the brain is a common finding in patients with neurodegenerative diseases, such as Alzheimers disease and Parkinsons disease, and can cause neurodegeneration prior to disease onset. The brain, which consumes high oxygen, is particularly vulnerable to oxidative stress caused by reactive oxygen species (ROS), against which Glutathione actively defends