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Quinone moiety Quinone moiety has also been utilized to develop hypoxia-triggered prodrug molecules owing to its ability to undergo electronic rearrangement to cleave covalent bonds under hypoxic conditions 123

Gamarra Y, Santiago FC, Molina-Lopez J, Castano J, Herrera-Quintana L, Dominguez A, Planells E

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The peak concentration observed during daytime within the vehicular tunnel for PM 10 reached 298 g/m 3 , while the maximum concentration within the tram tunnel was recorded at 127 g/m 3 (Fig