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Milk Thistle most commonly used to protect the liver from toxicity has also been shown in animal studies to enhance GSH production, as has turmeric

"Ibuprofen toxicosis in dogs, cats, and ferrets"

Thus, for longitudinal comparisons between the pretreatment baseline and post-treatment follow-up timepoints, including post-DBS, post-TMS and post-levodopa conditions, one-tailed paired t -tests were used, based on an a priori directional hypothesis that therapeutic STN-DBS, SCAN-targeted TMS and levodopa would reduce the SCAN hyperconnectivity observed in PD