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For instance, SIRT7 has been identified as a key player in the pathogenesis of immune-mediated intestinal inflammation, specifically in inflammatory bowel disease (IBD)

Carotenoids may upregulate the activity of antioxidant enzymes, mainly via the activation of the Nuclear factor erythroid 2-related factor 2 (Nrf2)-dependent pathway (Kaulmann and Bohn 2014)

Baseline characteristics of the non-interventional cohort of young adults and the interventional cohort of older adult volunteers are summarized in Table 1

The observed increase in hippocampal BDNF levels in Mg-citrate-treated groups, despite unchanged Mg concentrations in the hippocampus, may arise from systemic or indirect neural mechanisms rather than direct local Mg accumulation